Problems with Itunes on pC

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Joined: Jan 1 2005
Posts: 1

When i am listening to Itunes 4.7 on my PC (windows XP), there is a popping interference sound anytime I try to open other applications. This usually corresponds with 100% CPU usage. This used to never happen, but now it is. I have a pretty powerful machine, why is this happening? Any remedies?